Those images are interesting. I would expect the T24A to have a longer block since it's inline 4 vs the V35A V6. It looks like the image of the V35A has the fan and intake/intercooler plumbing included, but the T24A image does not. Maybe that's throwing me off? The T24A image makes it look like there's room for a 50% longer block, but like you say, the V35A image looks very tight.
I was pretty surprised when I saw how far back the T24A sits in the LC250. It seems The whole drivetrain, dash, and front seats sit further back in the F2 platform than previous generations. Neither the 4Runner or Tacoma have gained much interior space despite both having longer wheelbases than previous models. Why this is, I don't know. I assume it has something to do with crash regulations, but the set back drivetrain seems excessive.
Inline-6 engines used to be the go-to configuration for Land Cruisers, both for diesel and petrol engines. Here's a 100 series with a turbo 4.5L inline-6 in a IFS vehicle with sway bars.
I know we have stricter crash regulations now, but I still find it hard to believe Toyota can't figure out how to put an inline-6 in a BOF vehicle. The E-KDSS comment by the engineer just sounds like an excuse. It's not like inline-6 engines with sway bars haven't existed in the past. That first image shows the sway bar way in front of the engine.
The Ineos Grenadier uses the B58 petrol engine or B57 diesel engine. Here's a picture of the diesel engine bay. The engine is shoved up under the cowl a bit, but it doesn't seem much worse than the LC250 T24A.
If Lexus can cram a 2JZ in an IS300, they ought to be able to put an I-6 in a GX.