Select Lexus vehicles will be getting Apple CarPlay compatibility starting with the 2019 model year. The automotive iPhone interface will be added to the Lexus Enform 2.0 software, but does not appear to be backwards-compatible with existing vehicles already sold with that system.
Lexus parent company Toyota introduced CarPlay functionality at the Detroit Auto Show as part of the new Avalon sedan debut, and has confirmed to Apple website MacRumors that pre-2019 vehicles will not be upgraded “at this time”. It stands to reason this will be the case with Lexus vehicles as well.
CarPlay brings iOS functionality to your vehicle’s center console display — here’s a good overview of how the system works: